Constitutional diseases are here defined as malfunctions or pathological lesions whose etiology depends to a significant degree upon the action of genetic factors.

Constitutional means having to do with the document that is the foundation of a government — in the US, a constitutional right is one provided to you by the US Constitution.

Constitutional symptoms refers to a group of symptoms that can affect many different systems of the body. Examples include weight loss, fevers, headache, fevers of unknown origin, hyperhidrosis, generalized hyperhidrosis, chronic pain, fatigue, dyspnea, and malaise.

In constitutional medicine, the constitution of the person, or their inherent nature, comes into play. In 5 element theory, constitutional imbalance represents the most fundamental imbalance that can occur for someone.